| Fecha | Juego N° | Visitante | Carr | Carr | Home Club | Estadium | Box Score |
|---|---|---|---|---|---|---|---|
| 27/02/2021 | 1 | RGALLEGOS | 11 | 1 | TIBURONES | Toquita Mejias | BOX SCORE |
| 27/02/2021 | 2 | PENSIL | 12 | 8 | STARS | Toquita Mejias | BOX SCORE |
| 28/02/2021 | 3 | VENMEX | 4 | 4 | CARDENALES(S) | Toquita Mejias | BOX SCORE |
| 28/02/2021 | 4 | CARIBES | 7 | 3 | CARDENALES(M) | Toquita Mejias | BOX SCORE |
| 28/02/2021 | 5 | LEONES | 8 | 0 | DEPORTIVO | Toquita Mejias | BOX SCORE |
| 07/03/2021 | 7 | LEONES | 4 | 8 | RGALLEGOS | Jesus Rizalez | BOX SCORE |
| 07/03/2021 | 8 | CARDENALES(M) | 4 | 14 | VENMEX | Jesus Rizalez | BOX SCORE |
| 07/03/2021 | 9 | CARDENALES(S) | 10 | 10 | PENSIL | Toquita Mejias | BOX SCORE |
| 07/03/2021 | 10 | STARS | 2 | 3 | TIBURONES | Toquita Mejias | BOX SCORE |
| 20/03/2021 | 11 | PENSIL | 1 | 11 | CARDENALES(M) | Toquita Mejias | BOX SCORE |
| 21/03/2021 | 12 | TIBURONES | 7 | 3 | CARDENALES(S) | Jesus Rizalez | BOX SCORE |
| 21/03/2021 | 13 | RGALLEGOS | 10 | 3 | STARS | Jesus Rizalez | BOX SCORE |
| 21/03/2021 | 14 | VENMEX | 13 | 1 | DEPORTIVO | Toquita Mejias | BOX SCORE |
| 21/03/2021 | 15 | CARIBES | 14 | 3 | LEONES | Toquita Mejias | BOX SCORE |
| 01/05/2021 | 16 | CARDENALES(M) | 6 | 5 | TIBURONES | Toquita Mejias | BOX SCORE |
| 16/05/2021 | 17 | STARS | 2 | 6 | CARDENALES(S) | Toquita Mejias | BOX SCORE |
| 22/05/2021 | 18 | DEPORTIVO | 0 | 10 | PENSIL | Chico Carrasquel | BOX SCORE |
| 15/05/2021 | 19 | CARIBES | 6 | 2 | RGALLEGOS | Guamazo | BOX SCORE |
| 01/05/2021 | 20 | LEONES | 4 | 5 | VENMEX | Jesus Rizalez | BOX SCORE |
| 19/06/2021 | 22 | CARDENALES(M) | 8 | 7 | STARS | Jesus Rizalez | BOX SCORE |
| 16/05/2021 | 23 | TIBURONES | 3 | 1 | DEPORTIVO | Jesus Rizalez | BOX SCORE |
| 06/06/2021 | 24 | PENSIL | 6 | 9 | LEONES | Tronconal 5to | BOX SCORE |
| 22/05/2021 | 25 | VENMEX | 9 | 0 | CARIBES | Chico Carrasquel | BOX SCORE |
| 05/06/2021 | 27 | DEPORTIVO | 11 | 21 | STARS | Tronconal 5to | BOX SCORE |
| 30/05/2021 | 28 | CARIBES | 2 | 12 | PENSIL | Jesus Rizalez | BOX SCORE |
| 29/05/2021 | 29 | LEONES | 11 | 7 | TIBURONES | Jesus Rizalez | BOX SCORE |
| 30/05/2021 | 30 | VENMEX | 1 | 3 | RGALLEGOS | Jesus Rizalez | BOX SCORE |
| 13/06/2021 | 32 | VENMEX | 16 | 2 | PENSIL | Chico Carrasquel | BOX SCORE |
| 12/06/2021 | 33 | CARDENALES(S) | 17 | 16 | DEPORTIVO | Chico Carrasquel | BOX SCORE |
| 13/06/2021 | 34 | STARS | 11 | 14 | LEONES | Chico Carrasquel | BOX SCORE |
| 13/06/2021 | 35 | TIBURONES | 14 | 16 | CARIBES | Jesus Rizalez | BOX SCORE |
| 12/06/2021 | 36 | RGALLEGOS | 9 | 7 | CARDENALES(M) | Chico Carrasquel | BOX SCORE |
| 17/07/2021 | 37 | PENSIL | 3 | 2 | RGALLEGOS | El Guamazo Tronconal 3ro | BOX SCORE |
| 11/07/2021 | 39 | CARIBES | 10 | 1 | STARS | Jesus Rizalez | BOX SCORE |
| 17/07/2021 | 43 | CARDENALES(M) | 3 | 6 | LEONES | El Guamazo Tronconal 3ro | BOX SCORE |